DHEA is sometimes used under specialist care in IVF โ evidence is mixed
๐บ FertilityBy the Bloom Health Woman editorial team ยท Last updated October 2026 ยท Educational information, not medical advice. This page contains an affiliate link (see the product box). How we create content
DHEA is a hormone precursor. Some fertility clinics have offered it to people with diminished ovarian reserve who are having IVF, but trial results are mixed and systematic reviews describe the evidence as low-certainty. It acts as a hormone, can have androgenic side effects, and is only used under specialist supervision.
Only people whose fertility specialist has recommended it. Whether it suits you depends on your health, medicines and test results โ ask a clinician.
Clinical studies used about 25โ75 mg daily under medical supervision. Do not self-treat. This is not a recommendation. Doses vary by product and person; this is not personal medical advice.
Studies used pre-treatment of about 2โ3 months or longer before IVF.
Acne, oily skin, hair growth or loss, and voice changes can occur; it can also affect hormone-sensitive conditions.
Do NOT use without a fertility specialist. DHEA is a hormone and can cause hormonal side effects. Not suitable for people with PCOS (who often already have raised androgens) or hormone-sensitive cancers.
Evidence level (our editorial summary, not a formal grading): Limited / mixed.
Pregnancy & breastfeeding: Not for use during pregnancy.
Medication interactions: Can interact with hormone therapies and other medicines; do not combine without specialist advice.
Talk to a healthcare professional before use if you are pregnant, breastfeeding, planning pregnancy, have a medical condition, take any medicine, or are scheduled for surgery. Dietary supplements are not approved by the FDA for safety or effectiveness before they are sold, and quality varies between products.
Reliable sources to check: NIH Office of Dietary Supplements fact sheets ยท NCCIH Herbs at a Glance ยท MedlinePlus Herbs & Supplements ยท FDA โ Dietary Supplements
Optional product link. We have not tested this product and its inclusion is not a medical recommendation or an endorsement of any brand.
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