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Ovarian Reserve

DHEA (Dehydroepiandrosterone)

DHEA is sometimes used under specialist care in IVF โ€” evidence is mixed

๐ŸŒบ Fertility

By the Bloom Health Woman editorial team ยท Last updated October 2026 ยท Educational information, not medical advice. This page contains an affiliate link (see the product box). How we create content

๐Ÿ’ก What the Research Says

DHEA is a hormone precursor. Some fertility clinics have offered it to people with diminished ovarian reserve who are having IVF, but trial results are mixed and systematic reviews describe the evidence as low-certainty. It acts as a hormone, can have androgenic side effects, and is only used under specialist supervision.

๐Ÿ‘ฉ Who It Is Commonly Discussed For

Only people whose fertility specialist has recommended it. Whether it suits you depends on your health, medicines and test results โ€” ask a clinician.

โš—๏ธ Doses Used in Studies / Typical Label Amounts

Clinical studies used about 25โ€“75 mg daily under medical supervision. Do not self-treat. This is not a recommendation. Doses vary by product and person; this is not personal medical advice.

โฑ๏ธ Timeframes Reported

Studies used pre-treatment of about 2โ€“3 months or longer before IVF.

โš ๏ธ Possible Side Effects

Acne, oily skin, hair growth or loss, and voice changes can occur; it can also affect hormone-sensitive conditions.

๐Ÿšจ Important Warnings

Do NOT use without a fertility specialist. DHEA is a hormone and can cause hormonal side effects. Not suitable for people with PCOS (who often already have raised androgens) or hormone-sensitive cancers.

๐Ÿ›ก๏ธ Safety Snapshot

Evidence level (our editorial summary, not a formal grading): Limited / mixed.

Pregnancy & breastfeeding: Not for use during pregnancy.

Medication interactions: Can interact with hormone therapies and other medicines; do not combine without specialist advice.

Talk to a healthcare professional before use if you are pregnant, breastfeeding, planning pregnancy, have a medical condition, take any medicine, or are scheduled for surgery. Dietary supplements are not approved by the FDA for safety or effectiveness before they are sold, and quality varies between products.

Reliable sources to check: NIH Office of Dietary Supplements fact sheets ยท NCCIH Herbs at a Glance ยท MedlinePlus Herbs & Supplements ยท FDA โ€” Dietary Supplements

๐Ÿ“‹ Medical Disclaimer: This information is for educational purposes only and is not medical advice. Always consult your doctor or pharmacist before starting any supplement, especially if you are pregnant, breastfeeding, have a medical condition, or take medications. See our Medical Disclaimer.

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DHEA (Dehydroepiandrosterone)

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๐Ÿ“Š Quick Facts
๐Ÿท๏ธ Category: ๐ŸŒบ Fertility
โœ… Evidence (our summary): Limited / mixed