Magnesium Glycinate

Magnesium is a mineral involved in many body processes. Low magnesium is linked in some studies with insulin resistance, and some small trials in people with PCOS have looked at magnesium supplements, but evidence of benefit for PCOS symptoms is limited. A balanced diet usually provides enough.

People who are discussing options with a clinician, particularly if their diet is low in magnesium. Whether it suits you depends on your health, medicines and test results — ask a clinician.

Studies have used a range of doses, commonly 200–400 mg per day. The NIH upper limit for magnesium from supplements is 350 mg per day for adults; higher doses can cause diarrhea and should only be used on medical advice. Doses vary by product and person; this is not personal medical advice.

Studies measured effects over about 8–12 weeks.

Diarrhea, nausea and cramping, especially with magnesium oxide or higher doses. People with kidney disease should not take magnesium supplements without medical advice.

Reduce or stop if you get loose stools. Check with your doctor if you have kidney disease or take medicines affected by magnesium.

Evidence level (our editorial summary, not a formal grading): Limited.

Pregnancy & breastfeeding: Ask your provider before taking magnesium supplements in pregnancy.

Medication interactions: Can reduce absorption of some antibiotics (tetracyclines, quinolones), bisphosphonates and levothyroxine, and can interact with diuretics.

Talk to a healthcare professional before use if you are pregnant, breastfeeding, planning pregnancy, have a medical condition, take any medicine, or are scheduled for surgery. Dietary supplements are not approved by the FDA for safety or effectiveness before they are sold, and quality varies between products.

Reliable sources to check: NIH Office of Dietary Supplements fact sheets · NCCIH Herbs at a Glance · MedlinePlus Herbs & Supplements · FDA — Dietary Supplements